Thermo Fisher Scientific MEPE Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.0 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse MEPE/OF45 Ala17-Asp433 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEPE,uniProtId:Q8K4L6-1,ncbiNodeId:10090,antigenRange:17-433,antigenLength:441,antigenImageFileName:PA5-47817_MEPE_Q8K4L6-1_Sheep.svg,antigenImageFileNamePDP:PA5-47817_MEPE_Q8K4L6-1_Sheep_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2576224

Product Specific Information

In direct ELISAs, approximately 10% cross-reactivity with recombinant human MEPE/OF45 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases. MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines. It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.