Thermo Fisher Scientific DMGDH Polyclonal Antibody
Human DMGDH 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA557659
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DMGDH. Recombinant protein control fragment (Product #RP-96849). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640627 |
Product Specific Information
- Immunogen sequence:
IINVVNGPIT YSPDILPMVG PHQGVRNYWV AIGFGYGIIH AGGVGKYLSD WILHGEPPFD LIELDPNRYG KWTTTQYTE - Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 97%
Target Information
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine.
The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors.
Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-57659_DMGDH_Q9UI17-1_Rabbit.svg, PA5-57659_DMGDH_Q9UI17-1_Rabbit_PDP.jpeg)
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