Thermo Fisher Scientific HYAL2 Polyclonal Antibody
Human HYAL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20–1:50 희석 비율로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HYAL2. Recombinant protein control fragment (Product # RP-96270) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642593 |
Product Specific Information
Immunogen sequence:
APPIFTGRPF VVAWDVPTQD CGPRLKVPLD LNAFDVQASP NEGFVNQNIT IFYRDRLGLY PRFDSAGRSV HGGVPQNVSL WAHRK
Antigen sequence identity:
- Mouse: 81%
- Rat: 80%
Target Information
This gene encodes a weak acid-active hyaluronidase. The encoded protein is structurally similar to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, a major glycosaminoglycan of the extracellular matrix, and its fragments are involved in cell proliferation, migration, and differentiation.
Although previously thought to be a lysosomal enzyme active below pH 4, the encoded protein is likely a GPI-anchored cell surface protein. It also serves as a receptor for the oncogenic Jaagsiekte sheep retrovirus. The gene is located in chromosome region 3p21.3, associated with tumor suppression, and has two alternatively spliced transcript variants differing in the 5′ UTR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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