Thermo Fisher Scientific CHRNG Polyclonal Antibody
Thermo Fisher Scientific의 CHRNG Polyclonal Antibody는 인간 CHRNG 단백질을 인식하는 토끼 다클론 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CHRNG Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 257–489 of Human AChR gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548644 |
Product Specific Information
- Recommended positive controls: 293T, A431
- Predicted reactivity: Mouse (82%), Rat (82%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The mammalian muscle-type acetylcholine receptor (AChR) is a transmembrane pentameric glycoprotein composed of two alpha subunits, one beta, one delta, and one epsilon (adult skeletal muscle) or gamma (fetal and denervated muscle) subunit.
The CHRNG gene encodes the gamma subunit, expressed prior to the thirty-third week of gestation in humans. The gamma subunit plays a critical role in neuromuscular organogenesis and ligand binding.
Disruption of CHRNG expression prevents proper receptor localization in cell membranes. Mutations in this gene are associated with Escobar syndrome and a lethal form of multiple pterygium syndrome.
Muscle-type AChR is the major antigen in the autoimmune disease myasthenia gravis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.