Thermo Fisher Scientific WIPF1 Polyclonal Antibody
Human WIPF1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 IHC(P) 실험에 적합함. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 세포골격 형성 관련 연구용으로 사용.
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human WIPF1. Recombinant protein control fragment (Product #RP-102120). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649649 |
Product Specific Information
Immunogen sequence:
PPPPVSRNGS TSRALPATPQ LPSRSGVDSP RSGPRPPLPP DRPSAGAPPP PPPSTSIRNG FQDSPCEDEW ESRFYFHPIS DLPPPEPYVQ TTKSYPSKLA RNESRSGSNR RERGAP
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 90%
Target Information
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton.
The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder.
Impairment of the interaction between these two proteins may contribute to the disease.
Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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