Thermo Fisher Scientific Tara Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL
• Publications: -

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200
• Publications: -

Product Specifications

Product Specific Information

• Immunogen sequence:
  EIGALMRQAE EREHTLRRCQ QEGQELLRHN QELHGRLSEE IDQLRGFIAS QGMGNGCGRS NERSSCELEV LLRVKENELQ YLKKEVQCLR DELQMMQKDK RFTSGKYQDV YVELSHIKTR SEREIEQLKE HLRL
• Antigen sequence identity:
  • Mouse: 92%
  • Rat: 91%

Target Information

This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility, and cell growth. It also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene; however, some transcripts may be subject to nonsense-mediated decay (NMD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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