Thermo Fisher Scientific PEX3 Polyclonal Antibody
PEX3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC 실험에 최적화됨. 인간 및 다양한 종에 반응하며, Protein A로 정제된 1 mg/mL 액상 형태. Peroxin 3 연구 및 퍼옥시좀 생합성 관련 연구에 적합.
- 카탈로그번호
- PA542814
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 5 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Dog |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PEX3 (aa 31–80) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608452 |
Product Specific Information
- Peptide sequence: KYGQKKIREI QEREAAEYIA QARRQYHFES NQRTCNMTVL SMLPTLREAL
- Sequence homology:
Cow: 100% / Dog: 100% / Guinea Pig: 100% / Horse: 100% / Human: 100% / Mouse: 100% / Rabbit: 100% / Rat: 100% / Zebrafish: 93%
Target Information
Peroxin 3 (PEX3), also known as peroxisomal biogenesis factor 3 or TRG18, is a 373 amino acid multi-pass membrane protein localized to peroxisomes. It belongs to the Peroxin family and is expressed ubiquitously.
PEX3 interacts with Peroxin 19 and plays a critical role in peroxisome biosynthesis, membrane vesicle assembly, and maintenance of peroxisomal integrity.
It functions as a docking factor for Peroxin 19 and is essential for the import of peroxisomal proteins.
Defects in the PEX3 gene are associated with peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both resulting from impaired peroxisomal protein import.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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