Thermo Fisher Scientific IGF2BP2 Polyclonal Antibody
IGF2BP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체입니다. Western blot에 최적화되어 있으며, 인간 단백질에 반응합니다. 합성 펩타이드 면역원 사용, 액상 형태로 제공되며 -20°C 보관이 필요합니다.
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Applications
- Western Blot (WB): 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human IGF2BP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688938 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 100%; Yeast: 77%
Target Information
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several KH domains and two RRM domains. It functions by binding to the 5′ UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants encoding different isoforms have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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