Thermo Fisher Scientific NAE1 Monoclonal Antibody (OTI1A8), TrueMAB
인간 NAE1 단백질(아미노산 1-274)에 특이적인 Mouse IgG1 모노클로날 항체. Western blot에 적합하며, PBS/BSA/glycerol 저장용액에 1 mg/mL 농도로 제공. 세포주기 조절 및 Alzheimer’s 관련 연구에 활용 가능.
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Thermo Fisher Scientific NAE1 Monoclonal Antibody (OTI1A8), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–274 of human NAE1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties and is thought to play a role in the pathogenesis of Alzheimer’s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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