Thermo Fisher Scientific SLC25A14 Polyclonal Antibody
SLC25A14 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 ELISA에 적합하며, 인간, 마우스, 랫트 시료에 반응. 미토콘드리아 내막 단백질 검출에 유용. 고순도 친화 크로마토그래피 정제 항체.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| ELISA | 1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25–200 of human SLC25A14 (NP_001269124.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805543 |
Product Specific Information
- Positive Samples: Mouse brain, Rat brain
- Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein
Immunogen sequence:
GHQKSTTVSH EMSGLNWKPF VYGGLASIVA EFGTFPVDLT KTRLQVQGQS IDARFKEIKY RGMFHALFRI CKEEGVLALY SGIAPALLRQ ASYGTIKIGI YQSLKRLFVE RLEDETLLIN MICGVVSGVI SSTIANPTDV LKIRMQAQGS LFQGSMIGSF IDIYQQEGTR GLWRGV
Target Information
Mitochondrial uncoupling proteins (UCPs) are members of the mitochondrial anion carrier protein (MACP) family. UCPs separate oxidative phosphorylation from ATP synthesis, dissipating energy as heat (mitochondrial proton leak). They facilitate the transfer of anions and protons across the mitochondrial inner and outer membranes, reducing membrane potential in mammalian cells.
UCPs contain three homologous protein domains of MACPs. SLC25A14 is expressed in many tissues, with the highest levels in brain and testis, and features an N-terminal hydrophobic domain absent in other UCPs. Two splice variants have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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