Thermo Fisher Scientific PHLDA2 Polyclonal Antibody
PHLDA2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA에 사용 가능. Human 및 Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%) 항체로 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| ELISA | - | View 1 publication |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PHLDA2 (UniProt ID: Q53GA4-1, amino acids 1–152) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720597 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
TSSC3 (Tumor-suppressing STF cDNA 3 protein), also known as PHLDA2 (pleckstrin homology-like domain family A member 2), BWR1C, HLDA2, or IPL, is a cytoplasmic protein involved in fetal and placental growth. It is highly expressed in placenta and adult prostate, and at low levels in liver, lung, and brain. TSSC3 functions as an apoptosis-related protein and negative growth regulator expressed during normal development. It is maternally expressed and imprinted in placenta, liver, and fetal tissues during embryogenesis. Alterations in TSSC3 are associated with conditions such as lung, ovarian, and breast cancer, rhabdomyosarcoma, Beckwith-Wiedemann syndrome, Wilms tumor, low birth weight, and adrenocortical carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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