Thermo Fisher Scientific BRUCE Polyclonal Antibody
인간 BRUCE 단백질을 표적으로 하는 Rabbit IgG 폴리클로날 항체로, IHC에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 0.02% sodium azide를 포함합니다. 2–8°C에서 보관하며 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA534412
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific BRUCE Polyclonal Antibody
Applications
- Immunohistochemistry (IHC)
Tested Dilution: 5 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid synthetic peptide near the carboxy terminus of human BRUCE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551764 |
Product Specific Information
A suggested positive control is human small intestine tissue.
PA5-34412 can be used with blocking peptide PEP-1454.
Target Information
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases.
BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain.
BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-34412_BRUCE_Q9NR09-1_Rabbit.svg
- PA5-34412_BRUCE_Q9NR09-1_Rabbit_PDP.jpeg
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