Thermo Fisher Scientific ALK (Anaplastic Lymphoma Kinase)/CD246 Monoclonal Antibody (ALK/1503)
ALK 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot, ICC/IF, Flow Cytometry에 적합. 인간 ALK 단백질 조각을 면역원으로 사용. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ALK/1503 |
| Immunogen | Recombinant human ALK protein fragment (aa1360–1460) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily and plays a critical role in brain development. Mutations, rearrangements, and amplifications in the ALK gene are associated with various tumors, including anaplastic large cell lymphoma, neuroblastoma, and non-small cell lung cancer. Chromosomal rearrangements often lead to fusion genes such as NPM-ALK, which exhibit oncogenic properties. ALK is a receptor protein-tyrosine kinase with a transmembrane domain and extracellular region, showing high sequence similarity to LTK. It is essential for neuronal development and function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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