Thermo Fisher Scientific H-cadherin Polyclonal Antibody
H-cadherin 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot 및 IHC(P) 검증 완료. 인간 시료에 반응하며, 비결합형 액상 포맷으로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DSDRPERSKFRLTGK (aa 164–178) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933733 |
Product Specific Information
- The immunizing peptide represents the N terminus of the mature protein.
- This antibody is expected to recognize isoforms 1, 2, and 3 (NP_001248.1; NP_001207417.1; NP_001207418.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs.
It also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (FAST-1).
Reduced expression can suppress transforming growth factor-beta induced growth arrest.
Mutations in this gene are associated with increased risk of prostate cancer.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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