Thermo Fisher Scientific Thymidine Phosphorylase Monoclonal Antibody (PGF-44C)
Thymidine Phosphorylase 단일클론 항체(PGF-44C)는 인간 및 랫트 시료에서 사용 가능하며, WB, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 비결합형 액상 형태로 제공되며, -20°C 보관 및 Wet Ice 배송됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Not specified
- Publications: 2 available
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Not specified
- Publications: 1 available
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PGF-44C |
| Immunogen | Human platelet derived endothelial growth factor / thymidine phosphorylase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2533212 |
Target Information
Platelet-derived endothelial growth factor (PD-ECGF), also known as thymidine phosphorylase (TP) or gliostatin, catalyzes the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate in the presence of inorganic orthophosphate.
It is chemotactic and mitogenic for endothelial cells, functioning as a non-heparin binding angiogenic factor in platelets. Additionally, it plays a role in converting fluoropyrimidines—cytotoxic agents used in cancer treatment—into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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