Thermo Fisher Scientific RGS1 Polyclonal Antibody
RGS1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. Western blot 및 IHC에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS buffer에 20% glycerol 포함, 장기 보관 시 -20°C 권장.
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- PA529579
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–209 of Human RGS1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547055 |
Product Specific Information
- Recommended positive control: K562
- Predicted reactivity: Mouse (86%), Rhesus Monkey (97%), Bovine (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the regulator of G-protein signaling family.
The RGS1 protein is located on the cytosolic side of the plasma membrane and contains a conserved 120 amino acid RGS domain.
It attenuates G-protein signaling by binding to activated GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), accelerating GTP hydrolysis to GDP.
This process promotes formation of inactive G-protein heterotrimers, thereby terminating the signal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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