Thermo Fisher Scientific PSMA6 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji, mouse brain
• Predicted reactivity: Mouse (99%), Rat (100%), Xenopus laevis (89%), Pig (99%), Chicken (96%), Sheep (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure consists of four rings of 28 non-identical subunits: two rings of seven alpha subunits and two rings of seven beta subunits. Proteasomes are widely distributed in eukaryotic cells and are responsible for peptide cleavage in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome plays an essential role in processing class I MHC peptides. The PSMA6 gene encodes a 20S core alpha subunit belonging to the peptidase T1A family. A pseudogene has been identified on the Y chromosome.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.