Thermo Fisher Scientific Ethinylestradiol Polyclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Chemical

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Ethinylestradiol(3)-BTG

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

8.13 mg/mL

Purification

purified

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1090060

Product Specific Information

Working Concentration: 2.5 µg/mL. Sensitivity: 10 ng/mL Ethinyl Estradiol produces 86% inhibition in a competitive ELISA employing Ethinylestradiol polyclonal antibody.

Target Information

Ethinyl Estradiol is a semisynthetic alkylated estradiol with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in oral contraceptives. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. [National Center for Biotechnology Information. PubChem Compound Database; CID=5991].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.