ELK Biotechnology XRN1 rabbit pAb
XRN1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 세포질 내 국소화된 단백질 검출에 적합. 인간 및 마우스 시료 반응성. -20°C에서 1년 보관 가능.
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제품명
XRN1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 187 kD |
| Gene ID (Human) | 54464 |
| Human Swiss-Prot No | Q8IZH2 |
| Cellular Localization | Cytoplasm. Discrete foci at the inner surface of the cell membrane. |
| Species Reactivity | Human; Mouse |
제품 설명
This gene encodes a member of the 5′–3′ exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Sep 2013)
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