ELK Biotechnology CCNT2 rabbit pAb

제품명

CCNT2 rabbit pAb

공급업체

ELK Biotechnology

제품 설명

CCNT2 단백질은 세포 주기 조절에 관여하는 사이클린 패밀리에 속하며, CDK9과 함께 전사 신장 인자 p-TEFb 복합체의 구성 요소로 작용합니다. 이 항체는 인간 단백질에서 유래한 합성 펩타이드를 면역원으로 제작된 토끼 폴리클로날 항체입니다. WB 및 ELISA 분석에 사용되며, 세포질 및 핵 영역에서 CCNT2 단백질을 검출할 수 있습니다.

제품 스펙

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]