
ELK Biotechnology CAC1F rabbit pAb
인간 및 생쥐 반응성을 가지는 CAC1F rabbit polyclonal antibody로, WB와 ELISA에 적합합니다. 인간 단백질 유래 펩타이드(AA 140-220)를 면역원으로 사용하며, 고농도(1 mg/ml) IgG 포맷으로 제공됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
CAC1F rabbit pAb
주요 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 140–220) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 217 kD |
| Gene ID (Human) | 778 |
| Human Swiss-Prot No | O60840 |
| Cellular Localization | Membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse |
Background
Calcium voltage-gated channel subunit alpha1 F (CACNA1F) in Homo sapiens encodes a multipass transmembrane protein functioning as an alpha-1 subunit of the voltage-dependent calcium channel, mediating calcium ion influx into the cell. The encoded protein forms a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Mutations in this gene can cause X-linked eye disorders, including congenital stationary night blindness type 2A, cone-rod dystrophy, and Åland Island eye disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
(Provided by RefSeq, Aug 2013)
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