Thermo Fisher Scientific HECT domain of NEDD4 Polyclonal Antibody
NEDD4 단백질의 HECT 도메인을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC에 사용 가능하며 사람, 생쥐, 랫드 반응성. 동결건조 형태로 제공되며 연구용으로만 사용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Thermo Fisher Scientific HECT domain of NEDD4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the HECT domain of human NEDD4 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: NEDD4.
Target Information
The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein containing one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains.
It is involved in the degradation pathway of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity.
Acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, analogous to Mdm2 and p53.
Also involved in viral budding and regulation of epithelial Na⁺ channels, contributing to arterial hypertension.
NEDD4 protein localizes to the sarcolemmal region of muscle fibers. Increased expression is associated with unloaded and denervated muscles and decreased Notch1 expression, acting as a down regulator of Notch-1 gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Nexin 2 Polyclonal Antibody
563,100원
Thermo Fisher Scientific
Thermo Fisher Scientific Nexin 1 Polyclonal Antibody
563,100원
Thermo Fisher Scientific
Thermo Fisher Scientific HECT domain of NEDD4 Polyclonal Antibody
542,600원
Thermo Fisher Scientific
Thermo Fisher Scientific NDFIP2 Polyclonal Antibody
563,100원
Thermo Fisher Scientific
Thermo Fisher Scientific NDFIP1 Polyclonal Antibody
563,100원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|