Thermo Fisher Scientific TRPC5 Polyclonal Antibody
TRPC5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC에 적합하며, 인간 시료에 반응. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPC5 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPC5.
Target Information
TRPC5 belongs to the transient receptor family and is one of the seven mammalian TRPC (transient receptor potential channel) proteins.
The TRPC5 protein is a multi-pass membrane protein forming a receptor-activated non-selective calcium permeant cation channel.
It can act alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4.
TRPC5 interacts with multiple proteins including calmodulin, CABP1, enkurin, NHERF, MX1, RNF24, and SESTD1.
It operates via a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.
TRPC5 may also be activated by intracellular calcium store depletion.
Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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