ELK Biotechnology ATP5J rabbit pAb
ATP5J 단백질을 인식하는 토끼 폴리클로날 항체로, IHC 및 IF 분석에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 미토콘드리아 내막에 위치한 ATP 합성효소 복합체 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
ATP5J rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | IHC; IF |
| Recommended Dilutions | IHC-p 1:50–200 |
| Immunogen | Synthesized peptide derived from human ATP5J (AA range: 13–63) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 522 |
| Human Swiss-Prot No | P18859 |
| Cellular Localization | Mitochondrion; Mitochondrion inner membrane |
| Species Reactivity | Human; Mouse; Rat |
Background
Mitochondrial ATP synthase catalyzes ATP synthesis by utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core (F1) and the membrane-spanning component (Fo), which comprises the proton channel.
The F1 complex consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and one each of the other three subunits. The Fo complex contains nine subunits (a, b, c, d, e, f, g, F6, and 8).
This gene encodes the F6 subunit of the Fo complex, which is required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, and one or more pseudogenes exist (RefSeq, Feb 2016).
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