Thermo Fisher Scientific MIP-3 alpha Monoclonal Antibody (67310)
인간 MIP-3α(CCL20)을 인식하는 Mouse IgG1 단일클론 항체로 ELISA, Western blot, 중화 실험에 사용 가능. E. coli 유래 항원으로 제작되었으며 교차 반응 없음. 동결건조 형태로 제공되며 -20°C에서 보관.
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Thermo Fisher Scientific MIP-3 alpha Monoclonal Antibody (Clone 67310)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 2–8 µg/mL |
| Neutralization (Neu) | 1–5 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 67310 |
| Immunogen | E. coli-derived recombinant human CCL20/MIP-3 alpha Ala27–Met96 (Asn95Asp) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608262 |
Product Specific Information
- In ELISAs, this antibody does not cross-react with recombinant human CCL19, CXCL1, CCL16, CCL11, recombinant mouse CCL20, or recombinant rat CCL20.
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody (LAL method).
Target Information
Macrophage Inflammatory Protein-3 alpha (MIP-3α), also known as CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. It is upregulated by inflammatory signals and downregulated by IL-10.
MIP-3α signals through the CCR6 receptor and acts as a chemoattractant to lymphocytes and dendritic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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