
Thermo Fisher Scientific CD72/Ly-32 Polyclonal Antibody
CD72/Ly-32 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human CD72 (amino acids 4–110) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD72 is a transmembrane glycoprotein expressed as a homodimer, mainly in B cells and other antigen-presenting cells such as dendritic cells and macrophages. Through its immunoreceptor tyrosine-based inhibitory motifs (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1 to suppress B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72, resulting in dissociation of SHP-1 and subsequent B cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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