
Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI3D7), TrueMAB
Human NKX2-1 단백질을 인식하는 Mouse IgG1 단클론 항체로, ICC/IF 등 연구용에 적합. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol 버퍼에 보존. Affinity chromatography로 정제되어 높은 특이성과 안정성 제공.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D7 |
| Immunogen | Full length human recombinant protein of human NKX2-1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes. It also regulates genes involved in morphogenesis.
Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be linked to thyroid cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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