Thermo Fisher Scientific Kininogen 1 Polyclonal Antibody
Human Kininogen 1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KNG1. Recombinant protein control fragment (Product #RP-100525) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789118 |
Product Specific Information
Immunogen sequence:
ALKKYNSQNQ SNNQFVLYRI TEATKTVGSD TFYSFKYEIK EGDCPVQSGK TWQDCEYKDA AKAATGECTA TVGKRSSTKF SVATQTCQIT PAEGPVVTAQ YDCLGCVHPI STQSPDLEPI LRHGIQYFNN N
Target Information
The KNG1 gene produces two proteins via alternative splicing: high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK).
- HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system.
- Bradykinin, a peptide with multiple physiological effects, is released from HMWK.
- LMWK is not involved in blood coagulation.
Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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