Thermo Fisher Scientific Glutamine Synthetase Polyclonal Antibody
Thermo Fisher Scientific의 Glutamine Synthetase Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하는 토끼 IgG 폴리클로날 항체입니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관하며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
| Immunoprecipitation (IP) | 1:100–1:500 | – |
| In Situ Hybridization (ISH) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Fruit fly, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human Glutamine synthetase recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546416 |
Product Specific Information
- Recommended positive controls: 293T, U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse brain, mouse eye, rat brain
- Predicted reactivity: Mouse (94%), Rat (92%), Xenopus laevis (85%), Dog (97%), Pig (96%), Chicken (88%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays a central role in mammalian nitrogen flow, serving as both a nitrogen donor and acceptor. It also regulates neurotransmitter glutamate metabolism. GS activity is controlled by adenylylation and is decreased in the cerebral cortex of brains affected by Alzheimer’s disease and under glucose deprivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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