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Thermo Fisher Scientific PAR4 Polyclonal Antibody
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PAR4 단백질을 인식하는 Rabbit IgG 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 인간, 마우스, 랫트에서 반응하며, 고순도 Affinity Chromatography로 정제되었습니다. 세포 내 및 핵 위치에서 PAR4 단백질 검출에 유용합니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오전 06:34
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Thermo Fisher Scientific PA5120851 PAR4 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
710,700원VAT 포함 781,770원
Thermo Fisher Scientific · Thermo Fisher Scientific PAR4 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 200–300 of human PAR4 (NP_002574.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914423 |
Product Specific Information
- Positive test controls: BT-474, HT-29, SKOV3, SW480, HepG2
- Localization: Cytoplasm, Nucleus
- Immunogen sequence:
QNEAVNLLDP GSSYLLQEPP RTVSGRYKST TSVSEEDVSS RYSRTDRSGF PRYNRDANVS GTLVSSSTLE KKIEDLEKEV VRERQENLRL VRLMQDKEEM I
Target Information
This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms.
- Intracellular mechanism: Inhibition of pro-survival pathways and activation of Fas-mediated apoptosis
- Extracellular mechanism: Binding of secreted form to glucose regulated protein 78 (GRP78) on the cell surface, activating the extrinsic apoptotic pathway
Located on human chromosome 12q21, often deleted or mutated in tumors. Plays a role in age-related disease progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-120851_PAR4_Q96IZ0-1_Rabbit.svg 및 PA5-120851_PAR4_Q96IZ0-1_Rabbit_PDP.jpeg 이미지 포함)
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