Thermo Fisher Scientific Cathepsin L Polyclonal Antibody
Cathepsin L 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Cathepsin L (amino acids 114–288 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903512 |
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and myocardial ischemia, and in the renal tubular response to proteinuria. This protein, a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains produced from a single protein precursor. At least two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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