
Thermo Fisher Scientific PCDHGC5 Polyclonal Antibody
PCDHGC5 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트에 반응하며 Protein A로 정제된 고품질 항체입니다. 연구용으로 신경세포 간 결합 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PCDHGC5 (amino acids 121–220) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PCDHGC5 gene belongs to the protocadherin gamma gene cluster, one of three related clusters located on chromosome 5. These clusters exhibit an immunoglobulin-like organization, suggesting a unique regulatory mechanism.
The gamma gene cluster includes 22 genes divided into three subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region containing six cadherin ectodomains and a transmembrane region, while the constant region exons encode the common cytoplasmic region. These neural cadherin-like adhesion proteins are believed to play critical roles in establishing and maintaining specific cell-cell connections in the brain. Alternative splicing events have been reported for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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