
Thermo Fisher Scientific NXPH2 Polyclonal Antibody
NXPH2 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. 높은 특이성과 안정성을 제공하며, Protein A로 정제된 1 mg/mL 액상 형태로 공급. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NXPH2, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Neurexophilin-1 (NPH1 or NXPH1), Neurexophilin-2 (NPH2 or NXPH2), and Neurexophilin-3 (NPH3 or NXPH3) are members of the Neurexophilin family (Neurexophilin-1–4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis.
Neurexophilin-1–3 are secreted proteins functioning as signaling molecules that bind to target proteins such as neurexin I-alpha, which promotes adhesion between dendrites and axons and is essential for proper neurotransmitter release.
Neurexophilin-1 is primarily located in spleen tissue, Neurexophilin-2 is mainly expressed in kidney and brain, and Neurexophilin-3 is highly expressed in brain.
Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by abnormal perception of reality.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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