Thermo Fisher Scientific Caspase 7 p11 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human Caspase 7 p11 (aa 217–262). Validated for WB and ICC/IF. High purity (>95%) and antigen affinity purified. Supplied as liquid form at 1 mg/mL for apoptosis research applications.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 217–262 of Human Caspase 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803456 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
This gene encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce large and small subunits, which dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10, becoming activated upon cell death stimuli and inducing apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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