Thermo Fisher Scientific Glycerol-3-Phosphate Dehydrogenase Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot contents and freeze at -20°C or below.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as undiluted liquid.
• Dilute only prior to immediate use.

Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-goat serum, purified and partially purified Glycerol-3-Phosphate-Dehydrogenase [Rabbit Muscle].
Cross reactivity against Glycerol-3-Phosphate-Dehydrogenase from other sources is unknown.

Target Information

This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family.
The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and NADH to glycerol-3-phosphate (G3P) and NAD+.
The cytosolic and mitochondrial forms together form a glycerol phosphate shuttle facilitating transfer of reducing equivalents from cytosol to mitochondria.
Mutations in this gene cause transient infantile hypertriglyceridemia.
Alternatively spliced transcript variants encoding multiple isoforms have been observed.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.