Thermo Fisher Scientific CD171 Monoclonal Antibody (UJ181.4)
CD171(L1CAM) 단백질을 인식하는 UJ181.4 클론의 마우스 단클론 항체. Western blot, IHC, IP에 사용 가능. 인간 시료 반응성. 단백질 A/G 정제, PBS에 0.02% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific CD171 Monoclonal Antibody (UJ181.4)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | 1:10–1:500 | - |
| Immunoprecipitation (IP) | 1:10–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UJ181.4 |
| Immunogen | 16-week human fetal brain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1016755 |
Target Information
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin superfamily. The ectodomain consists of several immunoglobulin-like domains and fibronectin-like type III repeats, linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes collectively known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia, and hydrocephalus). Alternative splicing of a neuron-specific exon is functionally relevant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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