Thermo Fisher Scientific RING1 Polyclonal Antibody
RING1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot, IHC, IP 등 다양한 응용에 적합. 1 mg/mL 농도의 액상형으로 4°C 보관. 인간 및 영장류 종에서 반응 예측됨.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of Human Ring Finger Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Monkey, Gorilla, and Chimpanzee.
Target Information
RING1 belongs to the RING finger family, encoding proteins with a RING domain—a zinc-binding motif similar to the zinc finger domain. The gene product can bind DNA and function as a transcriptional repressor, associated with the polycomb group protein complex. It interacts with BMI1, EDR1, and CBX4, colocalizing in large nuclear domains. The CBX4 interaction occurs via the glycine-rich C-terminal domain. The gene maps to the HLA class II region, contiguous with RING finger genes FABGL and HKE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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