Thermo Fisher Scientific RING1 Polyclonal Antibody
RING1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 사용 가능. Human 반응성, 항원 친화 크로마토그래피 정제, 액상 형태, 4°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of Human Ring Finger Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, antibody predicted to react with Monkey, Gorilla, and Chimpanzee
Target Information
This gene belongs to the RING finger family, encoding proteins characterized by a RING domain—a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex and interacts with BMI1, EDR1, and CBX4, colocalizing with these proteins in large nuclear domains. It interacts with CBX4 via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, contiguous with RING finger genes FABGL and HKE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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