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Thermo Fisher Scientific NEDD4L Polyclonal Antibody
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Thermo Fisher Scientific의 NEDD4L Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로, 안정적인 4°C 보관이 가능합니다. 연구용으로만 사용됩니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오전 11:11
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Thermo Fisher Scientific A302513AT NEDD4L Polyclonal Antibody 10 ul pk판매 단위 pk ·
재고 확인 필요
194,600원VAT 포함 214,060원
Thermo Fisher Scientific · Thermo Fisher Scientific NEDD4L Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 and 325 of human neural precursor cell expressed, developmentally down-regulated 4-like |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
NEDD4L is an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 conjugating enzyme to targeted substrates. It inhibits TGF-beta signaling by promoting ubiquitination and degradation of SMAD2 and TGFR1. NEDD4L also regulates plasma membrane channels such as ENaC, Nav1.x, Kv1.3, EAAT1, and CLC5, and promotes degradation of SGK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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