Thermo Fisher Scientific DTX3L Polyclonal Antibody
DTX3L 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. IHC, ICC/IF, Flow, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적인 액상 형태로 연구용 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DTX3L Polyclonal Antibody
Thermo Fisher Scientific DTX3L Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human DTX3L, amino acids 651–740 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Component of the shelterin complex (telosome) that regulates telomere length and protection. Shelterin binds to double-stranded TTAGGG repeats added by telomerase and safeguards chromosome ends. Loss of shelterin activity exposes telomeres to DNA damage surveillance, leading to inappropriate processing by DNA repair pathways. Promotes POT1 binding to single-stranded telomeric DNA and modulates POT1’s inhibitory effects on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase and increasing its processivity. May play a role in organogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.