Thermo Fisher Scientific CD20 Polyclonal Antibody, Biotin
Biotin으로 표지된 Thermo Fisher Scientific CD20 다클론 항체로 인간 CD20 단백질을 인식합니다. Western blot 및 ELISA에 적합하며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용되며 안정적인 저장 버퍼와 항온 조건에서 보관 가능합니다.
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Applications
- Western Blot (WB): 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence: CQDQESSPIENDSSP (aa 284–297) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932651 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.
Target Information
CD20 is a non-glycosylated surface phosphoprotein with a molecular weight of 33–37 kDa depending on phosphorylation. It is expressed on mature and most malignant B cells, some T lymphocytes, and follicular dendritic cells. CD20 regulates transmembrane calcium conductance, cell cycle progression, and B-cell proliferation. It associates with lipid rafts and interacts dynamically with the B-cell antigen receptor (BCR). CD20 remains surface-bound after antibody binding, making it a valuable target for therapeutic B-cell depletion. Dysfunctions in CD20 are linked to Ms4a1-related common variable immune deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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