Thermo Fisher Scientific CSK Polyclonal Antibody, Biotin
CSK 단백질을 인식하는 Biotin 결합 폴리클로날 항체로 Western blot 및 IHC에 사용 가능. Human, Mouse, Rat에 반응하며 Goat IgG로 제작. 고순도 액상 형태로 안정적이며 연구용으로 적합.
- 카탈로그번호
- PA5141985
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific CSK Polyclonal Antibody, Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence CEQLEHIKTHELHL (aa 438–450) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932648 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:128,000.
Target Information
CSK is a tyrosine kinase that downregulates SRC oncoprotein activity through phosphorylation of its carboxy terminus. The CSK gene may act as an antioncogene and plays a key role in regulating cell growth, differentiation, migration, and immune responses.
CSK phosphorylates tyrosine residues in the C-terminal tails of Src-family kinases including LCK, SRC, HCK, FYN, LYN, CSK, and YES1.
It is ubiquitously expressed as a ~50 kDa cytosolic protein, with a fraction associated with lipid rafts via interaction with PAG (Csk-binding protein).
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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