Thermo Fisher Scientific IRS2 Polyclonal Antibody
인슐린 수용체 기질 2(IRS2)에 특이적인 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. ICC/IF 실험에 적합하며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human IRS2. Recombinant protein control fragment (Product #RP-106563) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2665252 |
Product Specific Information
Immunogen sequence:
ELYRLPPASAV ATAQGPGAAS SLSSDTGDNG DYTEMAFGVA ATPPQPIAAP PKPEAARVAS PTSGVKRLSL MEQVSGVEAF LQAS
Highest antigen sequence identity to the following orthologs:
- Mouse: 85%
- Rat: 84%
Target Information
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors.
The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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