Thermo Fisher Scientific Phospho-Smad3 (Ser208) Polyclonal Antibody
Phospho-Smad3 (Ser208) 항체로 인간, 마우스, 랫트 시료에서 인산화된 Smad3 검출에 적합. WB, IHC, ICC/IF 등 다양한 응용 가능. 고순도 정제 및 액상 형태로 제공되며, 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-Smad3 (Ser208) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human SMAD3 (Accession P84022), corresponding to amino acid residues around phosphorylated Ser208 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816007 |
Product Specific Information
Antibody detects endogenous levels of Smad3 only when phosphorylated at Serine 208.
Target Information
SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma.
SMAD proteins act as signal transducers and transcriptional modulators mediating multiple signaling pathways.
This protein functions as a transcriptional modulator activated by transforming growth factor-beta (TGF-β) and is thought to play a role in the regulation of carcinogenesis.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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