Thermo Fisher Scientific LMAN1 Monoclonal Antibody (OTI1B8), TrueMAB
LMAN1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 적합합니다. Human, Dog, Rat 시료에 반응하며 HEK293T 세포에서 발현된 full-length recombinant LMAN1을 면역원으로 제작되었습니다. 액상 형태로 -20°C 보관 권장.
- 카탈로그번호
- TA502269
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B8 |
| Immunogen | Full length human recombinant protein of human LMAN1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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