Thermo Fisher Scientific CAPN5 Monoclonal Antibody (OTI7F2), TrueMAB
CAPN5 단백질을 인식하는 Mouse IgG1 단클론 항체로, 인체 시료에 반응합니다. IHC(파라핀) 실험에 적합하며, 동결건조 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, 트레할로스 안정화 PBS 버퍼 포함.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 274–578 of human CAPN5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Calpains are calcium-dependent cysteine proteases involved in signal transduction and various cellular processes. A functional calpain protein consists of an invariant small subunit and one of a family of large subunits. CAPN5 is one of these large subunits. Unlike some calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Due to its similarity to the Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also known as HTRA3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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