Thermo Fisher Scientific MNAT1 Polyclonal Antibody
MNAT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MNAT1 (Accession P51948), corresponding to amino acid residues H28–V78 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851919 |
Product Specific Information
This antibody detects endogenous levels of total MNAT1.
Target Information
Progression through the cell cycle requires activation of cyclin-dependent kinases (Cdks). Cdk2, a key enzyme for cell cycle initiation, is inactive as a monomer and requires binding to regulatory cyclins (e.g., cyclin D1) and phosphorylation at Thr160 for full activation. The enzyme responsible for this phosphorylation, Cdk-activating kinase (CAK), consists of a catalytic subunit, a regulatory subunit, and a subunit of unknown function. The regulatory subunit, cyclin H, activates Cdk7. Mat1, a protein associated with the cyclin H–Cdk7 complex, is essential for forming an active Cdk–cyclin complex and participates in phosphorylation of Cdk activation domains and RNA polymerase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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