
Thermo Fisher Scientific Inhibin, alpha (INHA) (Gonadal Cell Marker) Monoclonal Antibody (INHA/4265)
인히빈 알파(INHA) 단백질을 표적하는 단클론 항체로, 인간 시료에서 면역조직화학(IHC) 분석에 적합합니다. 단백질 A/G로 정제된 액상 항체이며, 보존제 없이 PBS(pH 7.4)에 용해되어 있습니다. 생식세포 표지자 연구 및 종양 억제 관련 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | INHA/4265 |
| Immunogen | A synthetic peptide (around aa 73–96) of alpha-subunit of human inhibin A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum levels of inhibin can reflect the size of granulosa-cell tumors, making it a useful marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit expression is suppressed in poorly differentiated tumor cells. Expression varies across tissues, suggesting that inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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