Thermo Fisher Scientific IL17RB Polyclonal Antibody
IL17RB 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 적합하며, Protein A로 정제된 1 mg/mL 농도의 액상 제품입니다. PBS 기반 버퍼에 보존되며 연구용으로 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human IL17RB (aa 291–502) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% Glycerol, 0.2% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802730 |
Target Information
A number of cytokines belonging to the interleukin (IL)-17 family, including IL-17B, IL-17C, and IL-17E, have been identified. IL-17 is a potent proinflammatory cytokine involved in diseases such as rheumatoid arthritis, multiple sclerosis, and tumor growth. IL-17B, C, and E can induce proinflammatory responses but do not bind to the IL-17 receptor, suggesting the existence of additional IL-17R-related receptors. Receptors for IL-17B and IL-17E have been identified as EV127 (mouse) and IL-17Rh1 (human), respectively. IL-17E activates the NF-kB pathway and induces IL-8 production. IL-17Rh1 mRNA is highly expressed in kidney and liver, and moderately in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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