Thermo Fisher Scientific ZIP12 Polyclonal Antibody
ZIP12 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화성 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human ZIP12 aa 685–691 (extracellular) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% Glycerol, 0.2% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802735 |
Target Information
The zinc transporter ZIP12 (SLC39A12) is a member of the divalent ion transporter family. Zinc is an essential ion involved in cellular growth, development, and differentiation. The ZIP transporter family is divided into four subfamilies: I, II, LIV-1, and gufA. ZIP12 is a multipass membrane protein belonging to the LIV-1 subfamily. Elevated ZIP12 levels have been observed in airway inflammation and asthma, suggesting its role in promoting zinc uptake to reduce inflammation. Reduced zinc levels and ZIP12 mutations have been reported in some schizophrenia patients, indicating a potential link with this disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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